Protein Modification Reagents
Medchemexpress LLC APN-C3-PEG4-azide | 2183440-32-4 | 97.97% | C24H32N6O6 | 50 MG
APN-C3-PEG4-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
eMolecules Acid-PEG5-NHS ester | 1343476-41-4 | 100MG | Purity: 95%
Broadpharm | Acid-PEG5-NHS ester | 100MG | 1343476-41-4 | MFCD15204346 | MW:418.41
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Cayman Chemical GefItInIb-based PROTAC 3 25mg
A PROTAC comprised of gefitinib linked to VHL ligand 1; induces degradation of EGFR containing the activating mutation L858R or an exon 19 deletion (DC50s = 22.3 and 11.7 nM, respectively) but does not induce degradation of wild-type EGFR at ≤10 μM in cell-based assays
eMolecules Fmoc-NH-PEG11-CH2COOH | Broadpharm | 2629308-66-1 | MFCD30723257 | 781.893 | C39H59NO15 | 98.000 | OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 340377163
Fmoc-NH-PEG11-CH2COOH | Broadpharm | 2629308-66-1 | MFCD30723257 | 781.893 | C39H59NO15 | 98.000 | OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 340377163
![eMolecules endo-BCN-PEG2-acid | Broadpharm | 1993134-72-7 | | 353.415 | C18H27NO6 | 0.000 | OC(=O)CCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 50mg | 208940035](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2229716.JPG-250.jpg)
eMolecules endo-BCN-PEG2-acid | Broadpharm | 1993134-72-7 | | 353.415 | C18H27NO6 | 0.000 | OC(=O)CCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 50mg | 208940035
endo-BCN-PEG2-acid | Broadpharm | 1993134-72-7 | | 353.415 | C18H27NO6 | 0.000 | OC(=O)CCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 50mg | 208940035
Medchemexpress LLC Biotin-PEG11-Mal | 1646619-56-8 | 96.5% | C41H71N5O16S | 25 MG
Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs themselves consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. These molecules function by harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- PROTACs consist of two distinct ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Functions by harnessing the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC DBCO-mPEG (MW 5kDa) | 99.10% | 50 MG
DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups
Medchemexpress LLC TAMRA-PEG4-acid | 1909223-02-4 | 95.3% | C36H43N3O10 | 50 MG
TAMRA-PEG4-acid is a dye derivative of TAMRA containing 3 PEG units. This fluorescent dye is intended for research use only, suitable for laboratory chemicals and the manufacture of substances.
- Target: Fluorescent dye
- Molecular weight: 677.80
- Solubility in DMSO: 100 mg/mL (147.54 mM)
- Appearance: Liquid, brown to reddish brown
eMolecules m-PEG24-acid | Broadpharm | 125220-94-2 | MFCD13184958 | 1117.324 | C50H100O26 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O | 1g | 353441926
m-PEG24-acid | Broadpharm | 125220-94-2 | MFCD13184958 | 1117.324 | C50H100O26 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O | 1g | 353441926
Medchemexpress LLC Biotin-PEG-azide | 956494-20-5 | MFCD21363314 | 98.7% | 2000.00 | Not specified - polydisperse PEG derivative (no fixed chemical formula) | 50 MG
Biotin-PEG-azide (MW 2000) is a biotin-labeled polyethylene glycol derivative with a terminal azide functional group for bioorthogonal conjugation. The reagent is supplied as a powder and is intended for use in click-chemistry bioconjugation workflows, enabling efficient biotinylation of alkyne-containing molecules and surfaces for downstream affinity capture and detection.
- Contains terminal azide for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC).
- Peg spacer provides hydrophilicity and reduces nonspecific interactions.
- Average molecular weight 2000 Da (polydisperse polymer).
- High purity, suitable for research applications.
- Stable as a powder at -20°C for long-term storage.
- Useful for protein labeling, affinity capture, and general bioconjugation.
eMolecules Amino-PEG4-CH2CO2tBu | 864680-64-8 | MFCD28122943 | 1g
Broadpharm | Amino-PEG4-CH2CO2tBu | 1g | 254745387 | BP-22302 | 98.000 | 864680-64-8 | MFCD28122943 | 307.387 | C14H29NO6
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Medchemexpress LLC Cyanine5.5 alkyne chloride | 1628790-37-3 | 99.0% | 656.30 | 5 MG
Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). It can react with azides for click chemistry labeling.
- Near-infrared (NIR) fluorescent dye
- Suitable for click chemistry labeling
Medchemexpress LLC 6-FAM-PEG3-azide | 412319-45-0 | 98.1% | C29H28N4O9 | 10MG
6-FAM-PEG3-Azide is a fluorescent labeling reagent composed of a 6-carboxyfluorescein (6-FAM) dye linked to an azide via a PEG3 spacer. It is designed for covalent conjugation to alkyne-functionalized partners using copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC), enabling fluorescent labeling of oligonucleotides and other biomolecules.
- Fluorescent labeling with excitation 498 nm and emission 532 nm.
- PEG3 spacer improves water solubility and reduces steric hindrance.
- Azide functional group for CuAAC and SPAAC click chemistry.
- Solid, light yellow to yellow form stable when stored as powder at -20°C.
- High purity (~98.1%) suitable for analytical and labeling applications.